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Table 2 Cytotoxicity and effective concentrations of integrase inhibitors in the MT2 cell system

From: Study on suitable analysis method for HIV-1 non-catalytic integrase inhibitor

  CC50 (nM) EC50 (nM) SI value
BI 224436 > 50,000.00 28.72 > 1740.95
EVG 1263.50 < 0.51 > 2477.46
RAL 6423.61 0.58 11,075.19
DTG 1740.93 < 0.51 > 3413.60
  1. CC50, Half maximal cell cytotoxicity concentration; EC50, Half maximal effective concentration, SI value, Selectivity index, CC50/EC50
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