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Table 2 Cytotoxicity and effective concentrations of integrase inhibitors in the MT2 cell system

From: Study on suitable analysis method for HIV-1 non-catalytic integrase inhibitor

 

CC50 (nM)

EC50 (nM)

SI value

BI 224436

> 50,000.00

28.72

> 1740.95

EVG

1263.50

< 0.51

> 2477.46

RAL

6423.61

0.58

11,075.19

DTG

1740.93

< 0.51

> 3413.60

  1. CC50, Half maximal cell cytotoxicity concentration; EC50, Half maximal effective concentration, SI value, Selectivity index, CC50/EC50
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Virology Journal

ISSN: 1743-422X