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Table 1 Baseline characteristics of all peg-IFN-treated CHB patients

From: Serum HBV RNA correlated with intrahepatic cccDNA more strongly than other HBV markers during peg-interferon treatment

Characteristic All SR group NSR group P value
(N = 30) (N = 9) (N = 21) (SR vs. NSR)
Age, year (median) 26.57 ± 4.17 27.00 ± 3.08 26.38 ± 4.62 0.216
Gender (male/female) 18/12 8/1 10/11 0.03
HBV genotype (%)     0.614
 B 10 (33.3%) 3 (33.3%) 7 (33.3%)  
 C 20 (66.7%) 6 (66.7%) 14 (66.7%)  
ALT (U/L, median (range)) 120 (66.8–174.0) 131.0 (96.7–181.0) 115.0 (59.0–174.0) 0.380
HBV DNA (log10 IU/mL) 7.57 ± 1.10 7.52 ± 1.05 7.59 ± 1.15 0.878
HBsAg (log10 IU/mL) 3.78 ± 0.64 3.59 ± 0.49 3.86 ± 0.69 0.310
HBcrAg (log10 KU/mL) 5.41 ± 1.23 5.24 ± 1.45 5.48 ± 1.16 0.636
HBV RNA (log10 copies/mL) 7.73 ± 1.18 7.72 ± 1.42 7.75 ± 1.09 0.959
HBV cccDNA (copies/cell, median (range)) 33.8 (15.4–76.4) 30.0 (13.2–100.8) 34.4 (13.7–66.7) 0.946
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