From: Incidence and risk factors for high-level BK viruria: a single center study in China
Variates | All recipients n = 262 | Group A n = 35 | Group B n = 227 | \(\chi^{2} or t\) \(value\) | P value |
---|---|---|---|---|---|
Donors | |||||
Sex (n, %) | |||||
Male | 197, 75.2% | 28.80% | 169, 74.4% | 0.501 | 0.479 |
Female | 65, 24.8% | 7.20% | 58, 25.6% | ||
Age (n, %) | |||||
< 18 | 27, 10.3% | 3, 8.6% | 24, 10.6% | 0.618 | 0.734 |
18–59 | 232, 88.5% | 32, 91.4% | 200, 88.1% | ||
≥ 60 | 3, 1.1% | – | 3, 1.3% | ||
BMI (n, %) | |||||
< 18 kg/m2 | 27, 10.3% | 3, 8.6% | 24, 10.6% | 0.873 | 0.832 |
18–23.9 kg/m2 | 161, 61.5% | 24, 68.6% | 137, 60.4% | ||
24–27.9 kg/m2 | 64, 24.4% | 7.20% | 57, 25.1% | ||
≥ 28 kg/m2 | 10, 3.8% | 1, 2.9% | 9, 4.0% | ||
Donor type (n, %) | |||||
Live | 40, 15.3% | 4, 11.4% | 36, 15.9% | 21.7 | < 0.001 |
Brain death | 12, 4.6% | 1, 2.9% | 11, 4.8% | ||
Cardiac death | 138, 52.7% | 9, 25.7% | 129, 56.8% | ||
Brain-cardiac death | 72, 27.5% | 21, 60.0% | 51, 22.5% | ||
Serum creatinine (mean ± SD) | 93.2 ± 54.2 μmol/L | 94.5 ± 65.2 μmol/L | 93.0 ± 52.5 μmol/L | − 0.152 | 0.880 |
Left or right kidney | |||||
Left | 141, 53.8% | 19, 54.3% | 122, 53.7% | 0.004 | 0.952 |
Right | 121, 46.2% | 16, 45.7% | 105, 46.3% | ||
Recipients | |||||
Sex (n, %) | |||||
Male | 189, 72.1% | 22, 62.9% | 167, 73.6% | 1.731 | 0.188 |
Female | 73, 27.9% | 13, 37.1% | 60, 26.4% | ||
Age (n, %) | |||||
< 18 | 2, 0.8% | – | 2, 0.9% | 0.365 | 0.833 |
18–59 | 254, 96.9% | 34, 97.1% | 220, 96.9% | ||
≥ 60 | 6, 2.3% | 1, 2.9% | 5, 2.2% | ||
BMI (n, %) | |||||
< 18 kg/m2 | 36, 13.7% | 3, 8.6% | 33, 14.5% | 3.026 | 0.388 |
18–23.9 kg/m2 | 187, 7 1.4% | 28.80% | 159, 70.0% | ||
24–27.9 kg/m2 | 36, 13.7% | 3, 8.6% | 33, 14.5% | ||
≥ 28 kg/m2 | 3, 1.1% | 1, 2.9% | 2, 0.9% | ||
Dialysis (n, %) | |||||
Hemodialysis | 209, 79.8% | 25, 71.4% | 184, 81.0% | 2.382 | 0.304 |
Peritoneal | 51, 19.5% | 10, 28.6% | 41, 18.1% | ||
Others | 2, 0.8% | – | 2, 0.9% | ||
ATG/ATG-F (n, %) | |||||
No | 176, 67.2% | 18, 51.4% | 158, 69.6% | 4.543 | 0.033 |
Yes | 86, 32.8% | 17, 48.6% | 69, 30.4% | ||
AR (n, %) | |||||
No | 217, 82.8% | 23, 65.7% | 194, 85.5% | 8.313 | 0.004 |
Yes | 45, 17.2% | 12, 34.3% | 33, 14.5% | ||
DGF (n, %) | |||||
No | 215, 82.1% | 19, 54.3% | 196, 86.3% | 21.170 | < 0.001 |
Yes | 47, 17.9% | 16, 45.7% | 31, 13.7% | ||
Infection within 30 days after surgery (n, %) | |||||
Pulmonary infection | 14, 5.3% | 3, 8.6% | 11, 4.9% | 3.936 | 0.140 |
Urinary tract infection | 14, 5.3% | 4, 11.4% | 10, 4.4% | ||
Others | 233, 88.9% | 28.80% | 205, 90.7% | ||
Immune factors | |||||
Immunosuppressive maintenance regimen (n, %) | |||||
TAC + MMF + Preda | 259, 98.9% | 34, 97.1% | 225, 99.1% | 1.046 | 0.306 |
Others | 3, 1.1% | 1, 2.9% | 2, 0.9% | ||
Number of kidney transplants (n, %) | |||||
First | 258, 98.5% | 35, 100% | 222, 98.2% | 0.626 | 0.731 |
Second | 4, 1.5% | – | 4, 1.8% | ||
HLA mismatching(mean ± SD) | 2.0 ± 1.1 | 1.9 ± 1.2 | 2.0 ± 1.0 | 0.745 | 0.457 |
Cold ischemia time (mean ± SD) | 10.2 ± 4.7 h | 9.8 ± 4.2 h | 10.3 ± 4.8 h | 0.555 | 0.576 |
Warm ischemia time (mean ± SD) | 4.5 ± 1.3 min | 4.8 ± 1.2 min | 4.5 ± 1.3 min | − 1.466 | 0.149 |