Fig. 1
From: Elevated l-threonine is a biomarker for Lassa fever and Ebola
Levels of l-threonine in blood of viral hemorrhagic fever patients. a Intensity versus retention time plots for the H+H2O− adduct of l-threonine in the blood of febrile patients without Ebola, Ebola patients, non-febrile patients and Ebola convalescent patients. Inset shows the Intensity versus retention time plot of an authentic l-threonine standard. b Levels of l-threonine in samples from febrile patients that tested negative for Ebola (n = 12) were compared to samples from patients with Ebola (n = 29), non-febrile controls (n = 4) or Ebola convalescent patients (n = 27). c Levels of l-threonine in samples from febrile patients that tested negative for Lassa fever (n = 22) were compared to samples from patients with non-fatal (n = 12) or fatal Lassa fever (n = 16). Signal intensity of serum threonine values are presented as mean and SEM. Significance levels (p values from one way ANOVA) are ***p < 0.0005 and ****p < 0.0001