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Table 2 Distribution of oncogenic hr-HPV types and histological results among hr-HPV-positive/ASC-US women

From: Distribution of cervical lesions in high-risk HPV (hr-HPV) positive women with ASC-US: a retrospective single-center study in China

HPV types Histological results
Total Normal (n, %) LSIL (n, %) HSIL (n, %) CA (n, %) HSIL+ (n,%)
HPV16 401 97 (24.19) 51 (12.72) 234 (58.35) 19 (4.74) 253 (63.09)
HPV18 91 42 (46.15) 25 (27.27) 21 (23.08) 3 (3.30) 24 (26.37)
HPV33 40 11 (27.50) 6 (15.00) 22 (55.00) 1 (2.50) 23 (57.50)
HPV39 37 17 (45.95) 13 (35.14) 7 (18.92) 0 (0.00) 7 (18.92)
HPV51 36 16 (44.44) 7 (19.44) 13 (36.11) 0 (0.00) 13 (36.11)
HPV52 99 48 (48.48) 23 (23.23) 28 (28.28) 0 (0.00) 28 (28.28)
HPV53 40 29 (72.50) 5 (12.50) 6 (15.00) 0 (0.00) 6 (15.00)
HPV56 47 33 (70.21) 10 (21.28) 4 (8.51) 0 (0.00) 4 (8.51)
HPV58 108 38 (35.19) 31 (28.70) 39 (36.11) 0 (0.00) 39 (36.11)
HPV66 31 16 (51.61) 9 (29.03) 6 (19.35) 0 (0.00) 6 (19.35)
Othera 113 49 (43.36) 30 (26.55) 34 (30.09) 0 (0.00) 34 (30.09)
2 typesb 440 161 (36.59) 104 (23.64) 170 (38.64) 5 (1.14) 175 (39.77)
3 typesc 94 34 (36.17) 21 (22.34) 39 (41.49) 0 (0.00) 39 (41.49)
≥ 4 typesd 20 6 (30.00) 5 (25.00) 9 (45.00) 0 (0.00) 9 (45.00)
12 hr-HPVe 376 179 (47.61) 75 (19.95) 121 (32.18) 1 (0.27) 122 (32.45)
HC2 1245 637 (51.16) 250 (23.24) 347 (27.87) 11 (0.88) 358 (28.76)
ANYf 241 92 (38.17) 56 (23.24) 88 (36.51) 5 (2.07) 93 (38.59)
N 3459 1505 (43.51) 721 (20.84) 1188 (34.35) 45 (1.30) 1233 (35.65)
  1. ASC-US, atypical squamous cells of undetermined significance; HPV, human papillomavirus; hr-HPV, high-risk human papillomavirus; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; CA, cervical cancer; HSIL+, high-grade squamous intraepithelial lesion or worse
  2. aSingle hr-HPV infection except HPV16, 18, 33, 39, 51, 52, 53, 56, 58 and 66
  3. bDouble infections with hr-HPV
  4. cTriple infections
  5. d4 or more than kinds hr-HPV infections
  6. eInfection(s) with a pool of 12 other hr-HPV types (including HPV 31,33,35,39,45,51,52,56,58,59,66 and 68) that did not know the specific type of HPV (from Cobas 4800 HPV test)
  7. fhr-HPV infection that did not know the specific type of HPV (from Cervista HPV HR (Hologic) or Hybrid Capture 2 test)