Table 2 S gene mutations from the current study
HBV S gene region | Mutation | Accession number | HBsAg Sero status |
|---|---|---|---|
MHR (aa 99–169) | |||
‘a’ determinant region (aa 124–147) | T143M | MT185642 | Negative |
MT185646 | Negative | ||
M133T | MT185649 | ||
D144G | MT185649 | Positive | |
Outside ‘a’ determinant region (aa 99–123 and 148–169) | T114P | MT185645 | Negative |
MT185643 | Negative | ||
MT185647 | Negative | ||
A159V | MT185642 | Negative | |
MT185646 | Negative | ||
F158L | MT185643 | Negative | |
Downstream of the MHR (aa 170–207) | A194V | MT185650 | Negative |
MT185649 | Positive | ||
MT185648 | Negative | ||
Y206E | MT185642 | Negative | |
MT185646 | Negative | ||
S207K | MT185650 | Negative | |
MT185649 | Positive |