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Table 3 Viral nucleic acid negative-conversion within 14 days and not negative rate at last assay in different treatment groups

From: Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID‐19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series

Feature

Without Arbidol (n = 63)a

With Arbidol (n = 99)

p value

OR (95% CI)

Time to PCR negative in respiratory specimens

 ≤ 14 days (%)

35 (55.6)

72 (72.7)

0.028*

0.47 (0.24, 0.91)

 > 14 days (%)

28 (44.4)

27 (27.3)

0.028*

 

 Not negative (%)

9 (14.3)

5 (5.1)

0.049*

3.13 (1.00, 9.83)

 

Control (n = 32)

Other antiviral drugs (n = 31)

Arbidol only (n = 69)

Arbidol + other antiviral drugs (n = 30)

 ≤ 14 days (%)

14 (43.8)

21 (67.7)

53 (76.8)*b

19 (63.3)

 > 14 days (%)

18 (56.2)

10 (32.3)

16 (23.2)

11 (36.7)

Not negative (%)

6 (18.8)

3 (9.7)

5 (7.2)

0 (0.00)

  1. *Statistically significant p vaues
  2. aA minority of patients didn't accept nucleic acid detection after hospitalization
  3. bControl group versus Arbidol group: OR = 0.23, 95% CI 0.10–0.57, p = 0.002