Table 2 Basic clinical and epidemic features based on antiviral drugs usage (four groups)
Feature | Control (n = 45) | Other antiviral drugs (n = 45) | Arbidol only (n = 90) | Arbidol + other antiviral drugs (n = 40) |
|---|---|---|---|---|
Age [years, M (IQR)]a | 51 (40, 61) | 52 (45, 59) | 48 (36, 56) | 51 (38, 58) |
> 50 years (%) | 25 (55.6) | 27 (60.0) | 39 (43.3) | 20 (50.0) |
Male (%) | 22 (48.9) | 25 (55.6) | 52 (57.8) | 20 (50.0) |
Underlying disease (%)b | 7 (15.6) | 9 (20.0) | 13 (14.4) | 14 (35.0) |
Onset symptoms | ||||
Fever (%) | 27 (60.0) | 37 (82.2) | 77 (85.6) | 35 (87.5) |
Less than 3 onset symptoms (%)c | 29 (64.4) | 23 (51.1) | 57 (63.3) | 25 (62.5) |
Lab examination | ||||
WBC (× 109/ L, M (IQR)) | 5.3 (4.5, 6.2) | 4.9 (4.3, 6.1) | 5.4 (4.4, 6.5) | 5.7 (4.1, 7.2) |
Neutrophils % [M (IQR)] | 65.5 (57.2, 70.3) | 66.5 (61.5, 69.3) | 62.8 (55.9, 71.1) | 65.3 (54.4, 73.9) |
Lymphocyte % [M (IQR)] | 22.0 (16.9, 27.8) | 24.6 (20.4, 29.1) | 23.1 (17.6, 32.2) | 24.2 (18.0, 32.7) |
Platelet [× 109/L, M (IQR)] | 167.0 (143.0, 234.0) | 160.0 (130.8, 201.8) | 165.0 (142.5, 209.5) | 179.0 (150.5, 232.5) |
CT findings | ||||
Lung region distribution | ||||
Unilateral (%) | 1 (2.2) | 1 (2.2) | 1 (1.1) | 0 (0.0) |
Bilateral (%) | 44 (97.8) | 44 (97.8) | 89 (98.9) | 39 (97.5) |
Absence of lesion (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (2.5) |
Lesions feature | ||||
GGOsd | 18 (40.0) | 19 (42.2) | 41 (45.5) | 24 (60.0) |
Scattered patchy infiltration with interstitial alteration | 18 (40.0) | 21 (46.7) | 24 (26.7) | 8 (20.0) |
Consolidation | 1 (2.2) | 1 (2.2) | 7 (7.8) | 0 (0.0) |
More than one feature | 8 (17.8) | 4 (8.9) | 18 (20.0) | 7 (17.5) |
Other antiviral drugs | ||||
Oseltamivir (%) | 0 (0.0) | 41 (91.2) | 0 (0.0) | 39 (97.5) |
Ribavirin (%) | 0 (0.0) | 1 (2.2) | 0 (0.0) | 1 (2.5) |
Ganciclovir (%) | 0 (0.0) | 1 (2.2) | 0 (0.0) | 0 (0.0) |
Prezcobix (%) | 0 (0.0) | 1 (2.2) | 0 (0.0) | 0 (0.0) |
Oseltamivir + Ribavirin (%) | 0 (0.0) | 1 (2.2) | 0 (0.0) | 0 (0.0) |
Other treatments except for antiviral drugs | ||||
Antibiotics | 23 (51.1) | 31 (68.9) | 57 (63.3) | 28 (70.0) |
Chinese medicine (Lian Hua Qing Wen) | 36 (80.0) | 36 (80.0) | 73 (81.1) | 35 (87.5) |
Methylprednisolone | 0 (0.0) | 1 (2.2) | 1 (1.1) | 0 (0.0) |
Gamma immunoglobulin | 1 (2.2) | 0 (0.0) | 2 (2.2) | 0 (0.0) |