From: Viruses of protozoan parasites and viral therapy: Is the time now right?
Pathogen | Pathogen species | Virus (family/genus) | Genome | Genome size | Virion (shape/diameter) | Main ORFs | References |
---|---|---|---|---|---|---|---|
Leishmania | L. guyanensis L. brasiliensis L. shawi | LRV1 (Totiviridae/Leishmaniavirus) | Monopartite, linear dsRNA | 5.3 Kb | Icosahedral/~ 40 nm | CP and CP/RdRp | |
L. major L. aethiopica L. infantum L. tropica | LRV2 (Totiviridae/Leishmaniavirus) | Monopartite, linear dsRNA | 5.2 Kb | Icosahedral/~ 40 nm | CP and CP/RdRp | ||
L. martiniquensis | LmarLBV1 (unassigned /Leishbunyaviruses) | Tripartite, linear ssRNA(-) | 6.1 Kb (segment L) 1.2 Kb (segment M); 0.7 Kb (segment S) | Enveloped, spherical/~ 100 nm | ORF L; ORF M and ORF S | [99] | |
Giardia | G. duodenalis | GLV (Totiviridae/Giardiavirus) | Monopartite, linear dsRNA | 6.3 Kb | Icosahedral/ ~ 48 nm | CP and CP/RdRp (2 partially overlapping ORFS) | [63] |
Trichomonas | T. vaginalis | TVV (1–4) (Totiviridae/Trichomonasvirus) | Monopartite, linear dsRNA | 4.5–5 Kb | Icosahedral/~ 33 nm | CP and CP/RdRp (2 partially overlapping) | |
Cryptosporidium | C. parvum C. hominis C. felis C. meleagridis | CSpV1 (Partitiviridae/Cryspovirus) | Bi-segmented, linear dsRNA | 1.8 Kb (dsRNA1) 1.4 Kb (dsRNA2) | Icosahedral ~ 31 nm | RdRp (dsRNA1) and CP (dsRNA2) | |
Plasmodium | P. vivax | MaRNAV-1 (unassigned/narna-like virus) | Bi-segmented, linear ssRNA (+) | 2.9Â Kb (segment I) 2.6 Kbp (segment II) | No true virion | RdRp (segment I) and CP (segement II) | [33] |