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Table 4 Odds ratios and P-values of SLC10A1 gene polymorphism under recessive, dominant, co-dominant and additive models of inheritance

From: NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

Model Alleles aOR (95% CI) bOR (95% CI)
rs2296651
 Recessive Model mt/wt CT + wt/wt TT 1 (reference) 1 (reference)
mt/mt CC n/a 2.70 (0.29–24.78)
 Dominant Model mt/wt TC + mt/mt TT 1 (reference) 1 (reference)
wt/wt CC 0.18 (0.07–0.44) * 1.55 (0.70–3.43)
 Co-dominant model wt/wt CC + mt/mt TT 1 (reference) 1 (reference)
mt/wt TC 5.2 (2.1–12.8) * 0.85 (0.4–1.6)
 Additive model 1 mt/wt TC 1 (reference) 1 (reference)
mt/mt TT 5.23 (2.09–13.11) * 0.49 (0.20–1.16)
rs61745930
 Additive Model wt/wt TT 1 (reference) 1 (reference)
mt/mt CC 1.5 (0.7–3.2) 0.80 (0.4–1.6)
rs4646287
 Recessive  Model mt/wt TC + wt/wt TT 1 (reference) 1 (reference)
mt/mt TT n/a n/a
 Dominant Model mt/wt TC + mt/mt TT 1 (reference) 1 (reference)
wt/wt CC 0.81 (0.35–1.85) 1.31 (0.53–3.24)
 Co-dominant model wt/wt CC + mt/mt TT 1 (reference) 1 (reference)
mt/wt CT 1.10 (0.50–2.4) 0.96 (0.4–2.2)
 Additive model 1 mt/wt TC 1 (reference) 1 (reference)
mt/mt TT 1.34 (0.58–3.10) 0.65 (0.25–1.66)
  1. mt mutant type, wt wild type, Highlighted values represent statistically significant values. CI-confidence interval; “*” represent statistically significant model, p f < 0.05. aOR- odds ratios for controls vs cases; bOR- odds ratios HBeAg positive and HBeAg negative