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Table 3 Genotype, allele frequencies of SLC10A1 gene polymorphism in active and inactive cases

From: NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

SNP

Inactive CHB cases (n = 89)

Active CHB cases (n = 57)

†P-value

N (%)

Allele frequency

N (%)

Allele frequency

C

T

C

T

rs2296651

 

0.882

0.118

 

0.860

0.140

0.240

 CC

72 (80.9)

  

42 (73.7)

   

 CT

13 (14.6)

  

14 (24.6)

   

 TT

4 (4.5)

  

1 (1.8)

   

HWE-P‡

0.123

  

0.112

   

rs61745930

 

0.044

0.956

 

0.035

0.965

0.382

 TT

85 (95.5)

  

53 (93.0)

   

 CT

0

  

0

   

 CC

4 (4.5)

  

4 (7.0)

   

HWE-P‡

 

0.013

  

0.009

  

rs4646287

 

0.916

0.084

 

0.912

0.088

0.374

 CC

76 (85.4)

  

47 (82.5)

   

 CT

11 (12.4)

  

10 (17.5)

   

 TT

2 (2.2)

  

0

   

HWE-P‡

0.615

  

0.821

   
  1. HWE-P Hardy-Weinberg equation p-values, †P-values represents the chi-square test to compare genotype frequency between case-and control -subjects. P-values for chi-squared test for variant allelic frequency based on HWE, p < 0.05 depicts it not consistent with HWE
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Virology Journal

ISSN: 1743-422X