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Table 3 Genotype, allele frequencies of SLC10A1 gene polymorphism in active and inactive cases

From: NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

SNP Inactive CHB cases (n = 89) Active CHB cases (n = 57) P-value
N (%) Allele frequency N (%) Allele frequency
C T C T
rs2296651   0.882 0.118   0.860 0.140 0.240
 CC 72 (80.9)    42 (73.7)    
 CT 13 (14.6)    14 (24.6)    
 TT 4 (4.5)    1 (1.8)    
HWE-P 0.123    0.112    
rs61745930   0.044 0.956   0.035 0.965 0.382
 TT 85 (95.5)    53 (93.0)    
 CT 0    0    
 CC 4 (4.5)    4 (7.0)    
HWE-P   0.013    0.009   
rs4646287   0.916 0.084   0.912 0.088 0.374
 CC 76 (85.4)    47 (82.5)    
 CT 11 (12.4)    10 (17.5)    
 TT 2 (2.2)    0    
HWE-P 0.615    0.821    
  1. HWE-P Hardy-Weinberg equation p-values, P-values represents the chi-square test to compare genotype frequency between case-and control -subjects. P-values for chi-squared test for variant allelic frequency based on HWE, p < 0.05 depicts it not consistent with HWE