Heterologous prime-boost: an important candidate immunization strategy against Tembusu virus

Table 1 Experimental designs of the animal studies

Groups	Number of animals/ducks	Prime (7 days)			Boost (19 days)			Challenge (31 days)
Groups	Number of animals/ducks	Vaccine	Dosage	Route	Vaccine	Dosage	Route	Numbers of animals^j	Challenge dosage
ads/ads^a	34	ads^f	10⁷PFU/0.5 ml	Intramuscular	ads	10⁷PFU/0.5 ml	Intramuscular	10	10^5.1ELD₅₀/1 ml
SE/SE^b	34	SE^g	10¹⁰CFU/0.5 ml	Oral injection	SE	10¹⁰CFU/0.5 m	Oral injection	10	10^5.1ELD₅₀/1 ml
SE/ads^c	34	SE	10¹⁰CFU/0.5 ml	Oral injection	ads	10⁷PFU/0.5 ml	Intramuscular	10	10^5.1ELD₅₀/1 ml
WF/WF^d	34	WF^h	0.5 mlⁱ	Intramuscular	WF	0.5 ml	Intramuscular	10	10^5.1ELD₅₀/1 ml
PBS/PBS^e	34	PBS	0.5 ml	Intramuscular	PBS	0.5 ml	Intramuscular	10	10^5.1ELD₅₀/1 ml

ISSN: 1743-422X