Table 1 Antibody or serum neutralizing activities by cell type
Species | Serum or antibody | targeta | neutralization IC50(ng/mL) | IC50ratio (endothelial/epithelial) | |
|---|---|---|---|---|---|
epithelial | endothelial | ||||
human | serum 1 | pan CMV | 682 | 788.3 | 1.16 |
serum 2 | 2609 | 2625 | 1.01 | ||
serum 3 | 2787 | 4557 | 1.64 | ||
serum 4 | 791 | 4557 | 5.75 | ||
serum 5 | 1769 | 3742 | 2.12 | ||
serum6 | 1467 | 1052 | 0.72 | ||
serum 7 | 710 | 552.2 | 0.78 | ||
serum 8 | 725 | 924.8 | 1.28 | ||
HIGd | 105 | 70.0 | 0.67 | ||
TRL345 | gB | 91.0 | 95.4 | 1.05 | |
TRL310 | PC | 0.286 | 0.318 | 1.11 | |
2–25 | 0.525 | 0.374 | 0.71 | ||
rabbit | 57.4 | 22.9 | 19.7 | 0.86 | |
276.1 | 34.8 | 24.7 | 0.71 | ||
α-UL130b | PC (UL130) | 1429c | 685c | 0.48 | |
α-UL131b | PC (UL131A) | 62.6c | 87.9c | 1.40 | |
15.1 | gH | 121 | 116 | 0.96 | |
58.5 | 209 | 220 | 1.05 | ||
223.4 | 156 | 240 | 1.54 | ||
347.3 | 391 | 292 | 0.75 | ||
70.7 | 36.5 | 29.5 | 0.81 | ||
124.4 | gH/gL | 67.5 | 49.1 | 0.73 | |
270.7 | 36.7 | 19.2 | 0.52 | ||
316.2 | 49.8 | 34.2 | 0.69 | ||
324.4 | 79.4 | 50.8 | 0.64 | ||