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Table 1 Antiviral activity of ACV and Aspergillipeptide D

From: Anti-HSV-1 activity of Aspergillipeptide D, a cyclic pentapeptide isolated from fungus Aspergillus sp. SCSIO 41501

Compound

CC50b(μM)

EC50c(μM)

HSV-1/F

HSV-1/106

HSV-1/153

HSV-1/Blue

ACVa

> 500

3.606 ± 0.302

46.234 ± 15.335

85.746 ± 21.753

273.742 ± 20.826

Aspergillipeptide D

208.723 ± 9.717**

7.928 ± 0.511

10.486 ± 0.929**

8.277 ± 1.249**

7.9875 ± 0.616**

  1. a Acyclovir
  2. b The CC50 (50% cytotoxic concentration for Vero cells in lg/ml); mean ± S.E
  3. c The EC50 (Concentration of compound producing 50% inhibition of virus-induced cytopathic effect)
  4. **represents a significant difference compered with the control group
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Virology Journal

ISSN: 1743-422X