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Table 1 Antiviral activity of ACV and Aspergillipeptide D

From: Anti-HSV-1 activity of Aspergillipeptide D, a cyclic pentapeptide isolated from fungus Aspergillus sp. SCSIO 41501

Compound CC50b(μM) EC50c(μM)
HSV-1/F HSV-1/106 HSV-1/153 HSV-1/Blue
ACVa > 500 3.606 ± 0.302 46.234 ± 15.335 85.746 ± 21.753 273.742 ± 20.826
Aspergillipeptide D 208.723 ± 9.717** 7.928 ± 0.511 10.486 ± 0.929** 8.277 ± 1.249** 7.9875 ± 0.616**
  1. a Acyclovir
  2. b The CC50 (50% cytotoxic concentration for Vero cells in lg/ml); mean ± S.E
  3. c The EC50 (Concentration of compound producing 50% inhibition of virus-induced cytopathic effect)
  4. **represents a significant difference compered with the control group
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Virology Journal

ISSN: 1743-422X