Differential expression of human papillomavirus 16-, 18-, 52-, and 58-derived transcripts in cervical intraepithelial neoplasia

Table 2 Clinical features according to HPV type

	HPV 16	HPV 18	HPV 52	HPV 58	Other hrHPVs	Negative	p-value
Age (years)	37 ± 0.9	39 ± 3.6	38 ± 0.8	39 ± 1.0	44 ± 1.2	40 ± 1.7	0.001^*1
Months since diagnosis	40 ± 5.2	38 ± 10.0	36 ± 4.4	39 ± 5.1	37 ± 7.2	37 ± 7.0	0.95^*1
Smoking (%)	15/55 (27.3)	3/10 (30.0)	14/56 (25.0)	19/56 (28.4)	16/72 (22.2)	7/39 (18.0)	0.57^*2
Parity ≥1 (%)	23/57 (40.3)	3/10 (30.0)	23/56 (41.1)	22/57 (38.6)	26/74 (35.1)	15/40 (37.5)	0.97^*2
Steroid use (%)	0/59 (0.0)	0/10 (0.0)	2/57 (3.5)	2/58 (3.5)	2/74 (2.7)	1/36 (2.8)	0.56^*2

Clinical features were summarized according to HPV categorize. HPVs 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68 were classified as hrHPVs. Of these, HPV 16, 18, 52, and 58 were categorized separately. hrHPVs other than HPVs 16, 18, 52, and 58 were classified as “other hrHPVs.” Patients who were not infected with any hrHPVs were referred to as “no hrHPVs” patients. Statistical analysis was performed using a Steel-Dwass test (*1) and the Analysis of Variance (*2)
HPV human papillomavirus

ISSN: 1743-422X