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Table 3 Presence of herpesviruses DNA according to the different chemotherapy phases as detected by multiplex PCR

From: Co-infections of human herpesviruses (CMV, HHV-6, HHV-7 and EBV) in non-transplant acute leukemia patients undergoing chemotherapy

Viral detection

Before chemotherapy

N = 95 (%)

Post- induction

N = 95 (%)

Post -remission

N = 70 (%)

After salvage

N = 29 (%)

All periods

N = 289 (%)

CMV

8 (8.4)

14 (14.7)

19 (27.1)

15 (51.7)

56 (19.4)

EBV

1 (1)

3 (3.15)

2 (2.8)

2 (7)

8 (2.7)

HHV-6

1 (1)

8 (8.4)

9 (12.9)

10 (34.5)

28 (9.7)

HHV-7

1 (1)

6 (6.3)

3 (4.2)

5 (17.2)

15 (5.2)

Patients negative for all

86 (90.5)

74 (78)

46 (65.7)

7 (24.1)

213 (73.7)

Patients positive for 1 or more detection

9 (9.5)

21 (22)

24 (34.3)

22 (75.9)

76 (26.3)

  1. The prevalence of viral infections during the different phases of chemotherapy: before chemotherapy, post-induction, post-remission and after salvage