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Table 1 Comparative ROC analysis of milk samples with 90 min and overnight incubation time using Youden and maximum specificity as criteria

From: Suitability of individual and bulk milk samples to investigate the humoral immune response to lumpy skin disease vaccination by ELISA

Criterion Youden Maximum specificity
Incubation 90 min overnight 90 min overnight
Area under ROC curve (ACU) 0.961 (0.942, 0.98) 0.932 (0.887, 0.977) 0.959 (0.939, 0.978) 0.92 (0.87, 0.971)
cut-off 1.308 3.086 9.425 9.785
Se 0.895 0.882 0.513 0.632
Sp 0.891 0.914 1.0 1.0
PPV 0.591 0.644 1.0 1.0
NPV 0.980 0.978 0.921 0.939
DLR. Positive 8.186 10.222 Inf Inf
DLR. Negative 0.118 0.13 0.487 0.368
FP 47.0 37.0 0.0 0.0
FN 8.0 9.0 37.0 28.0
Optimal criterion 0.785 0.795