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Table 5 The area under ROC curve of HPV DNA assay, HPV E6/E7mRNA testing, HPV E6/E7mRNA and p16/Ki-67 immunocytochemistry

From: Prognostic and diagnostic validity of p16/Ki-67, HPV E6/E7 mRNA, and HPV DNA in women with ASCUS: a follow-up study

Test

AUC

95% CI

HPV DNA

0.565

(0.430–0.700)

HPV E6/E7 mRNA

0.585

(0.444–0.725)

HPV E6/E7 mRNA expression

0.593

(0.456–0.731)

p16/Ki67

0.779

(0.649–0.908)

  1. AUC the area under the curve. Results in % with 95% confidence interval (95% CI). HPV E6/E7 mRNA expression means that 2097.09 copies/ml act as cut-off value to judge negative and positive of HPV E6/E7 mRNA testing and calculate the AUC