Table 3 Amino acid differences between the wild-type strain G1 and the mouse-adapted strain G1-MA

PB2

590^a

S

R

G (97.5%)

S (100%)

S (85%)

T (47%)

S (45%)

G (8%)

G(15%)

S (2.5%)

PA

349^c

E

K

E (100%)

E (100%)

E (100%)

E (100%)

486

I

M

I (100%)

I (100%)

I (100%)

I (100%)

HA

204 (196)^{b c}

I

M

T (95%)

T(60%)

/

/

K (4.2%)

I (40%)

A (0.6%)

I (0.2%)

206 (198)

N

T

T (95%)

T (60%)

/

/

A (4.2%)

N (0.8%)

N (40%)

271 (263)

G

E

E (99%)

E (60%)

/

/

G (0.5%)

V (0.5%)

G (40%)

M1

198

Q

H

Q (100%)

Q (100%)

Q (99%)

Q (100%)

H (1%)

239

A

T

A (100%)

A (100%)

A (100%)

T (97%)^d

A (2%)

V (1%)

M2

91

C

F

F (99.8%)

F (100%)

F (51%)

F (100%)

T (47%)

V (1%)

C (0.2%)

L (1%)

93

I

N

N (99.5%)

N (100%)

N (89%)

S (99%)

I (0.1%)

K (0.1%)

S (0.1%)

T (0.1%)

S (9%)

D (1%)

N (1%)

T (1%)