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Table 2 Viral distribution of wild-type and mouse-adapted viruses in different tissues in mice

From: Mouse-adapted H9N2 avian influenza virus causes systemic infection in mice

Virus

Mean virus titer in sample [log10 TCID50 ml−1] ± SD

Lung

Liver

Spleen

Kidney

Brain

G1

3/3a

-b

(5.6 ± 0.6)

    

G1-MA

3/3

(6.9 ± 0.3c)

    

ZB

3/3

(5.0 ± 0.1)

    

ZB-MA

3/3

2/3

3/3

2/3

3/3

(7.0 ± 0.1d)

(2.6 ± 0.1)

(3.3 ± 0.1)

(3.1 ± 0.2)

(3.7 ± 0.2)

  1. aNo. of infected mice/total no. of mice
  2. bNo virus was isolated from the sample
  3. cThe lung titers in the G1-MA group were significantly higher than those in the G1 group (p < 0.05)
  4. dThe lung titers in the ZB-MA group were significantly higher than those in the ZB group (p < 0.05)