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Table 2 HPV detection between HPV DNA Array and Cobas, stratified by age, histology, and cytology

From: CIN2+ detection of the HPV DNA Array genotyping assay in comparison with the Cobas 4800 HPV test and cytology

   Cobas
HPV DNA Array Positive Negative Agreement Kappa Interpretationa McNemar’s p
Overall population (499) Positive 329 2 81.4% 0.613 good 0.000
Negative 75 93
< 30 (217)b Positive 163 0 86.2% 0.618 good 0.000
Negative 26 28
≥30 (276) b Positive 164 2 77.4% 0.593 moderate 0.000
Negative 48 62
CIN2+ (22) Positive 22 0 100%    
Negative 0 0
HGSIL (8) Positive 8 0 100%    
Negative 0 0    
  1. aInterpretation values: poor (< 0.20), fair (0.21–0.40), moderate (0.41–0.60), good (0.61–0.80), very good (0.81–1.00)
  2. b6 samples, for which the age information was unavailable, were excluded from the analysis