Virology Journal

Table 2 HPV detection between HPV DNA Array and Cobas, stratified by age, histology, and cytology

From: CIN2+ detection of the HPV DNA Array genotyping assay in comparison with the Cobas 4800 HPV test and cytology

		Cobas
	HPV DNA Array	Positive	Negative	Agreement	Kappa	Interpretation^a	McNemar’s p
Overall population (499)	Positive	329	2	81.4%	0.613	good	0.000
Overall population (499)	Negative	75	93	81.4%	0.613	good	0.000
< 30 (217)^b	Positive	163	0	86.2%	0.618	good	0.000
< 30 (217)^b	Negative	26	28	86.2%	0.618	good	0.000
≥30 (276) ^b	Positive	164	2	77.4%	0.593	moderate	0.000
≥30 (276) ^b	Negative	48	62	77.4%	0.593	moderate	0.000
CIN2+ (22)	Positive	22	0	100%
CIN2+ (22)	Negative	0	0	100%
HGSIL (8)	Positive	8	0	100%
HGSIL (8)	Negative	0	0	100%

^aInterpretation values: poor (< 0.20), fair (0.21–0.40), moderate (0.41–0.60), good (0.61–0.80), very good (0.81–1.00)
^b6 samples, for which the age information was unavailable, were excluded from the analysis

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ISSN: 1743-422X

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