Fig. 1

Genotype I and II PRV pUL56 contains identical C-terminal transmembrane helices. a Alignment of pUL56 sequences between genotype I and II PRV strains shows 44 identical amino acids (163–207) at the C terminus (blue rectangle). Differential amino acids are indicated by red rectangles. b The 177–203 aa in pUL56 is identified as a helix structure, as predicted by PSIPRED. c Helical wheel displaying a hydrophobic character of the helix