Table 8 Genotype and allele frequencies of IL-β, IL17, IL10 and IL28 in influenza (A & B) and ILI groups
Gene and genotype | Flu A & B (%) | ILI (%) | Crude p value | OR (95% CI) | Adjusted p value | ||
|---|---|---|---|---|---|---|---|
IL-1β; rs16944 | |||||||
 AA | 7(22.6) | 24(77.4) |  |  |  | ||
 GA | 71(51.4) | 67(48.6) | .007* |  |  | ||
 GG | 2(33.3) | 4(66.7) |  |  | .027* | ||
 GG vs. GA/AA | 2(33.3) | 78(46.2) | 4(66.7) | 91(53.8) | .689 | .547 (.096–3.127) |  |
 AA vs. GG/GA | 7(22.6) | 73(50.7) | 24 (77.4) | 71(49.3) | .004* | .235 (.091–.610) |  |
 A | 85 | 115 | .163 | 1.353 (.884–2.070) |  | ||
 G | 75 | 75 |  |  |  | ||
IL-17; rs2275913 | |||||||
 AA | 6(40) | 9(60) |  |  |  | ||
 AG | 26(32.5) | 54(67.5) | .006* |  | .019* | ||
 GG | 44(57.9) | 32(42.1) |  |  |  | ||
 GG vs. GA/AA | 44(57.9) | 32(33.7) | 32(42.1) | 63(66.3) | .002* | 2.589 (1.3714.889) |  |
 AA vs. AG/GG | 6(40) | 70(44.9) | 9(60) | 86(55.1) | .717 | .810 (.266–2.467) |  |
 A | 38 | 72 | .011* | 1.831 (1.144–2.928) |  | ||
 G | 114 | 118 |  |  |  | ||
IL-10; rs1800872 | |||||||
 GG | 4(50) | 4(50) | .760 |  |  | ||
 TG | 72(48.3) | 77(51.7) |  |  |  | ||
 TT | 4(36.4) | 7(63.6) |  |  | .510 | ||
 TT vs. GG/TG | 4(36.4) | 76(48.4) | 7(63.6) | 81(51.6) | .439 | .619 (.170–2.256) |  |
 GG vs. TG/TT | 4(50) | 76(47.5) | 4(50) | 84(52.5) | 1.000 | .731 (.168–3.178) |  |
 G | 80 | 85 | .755 | .934 (.609–1.433) |  | ||
 T | 80 | 91 |  |  |  | ||
IL-28; rs8099917 | |||||||
 GG | 2(33.3) | 4(66.7) |  |  |  | ||
 GT | 42(46.7) | 48(53.3) | .889 |  | |||
 TT | 36(45.6) | 43(54.4) |  |  | .784 | ||
 TT vs. GG/GT | 36(45.6) | 44(45.8) | 43(54.4) | 52(54.2) | .972 | .882 (.474–1.641) |  |
 GG vs. GT/TT | 2(33.3) | 78(46.2) | 4(66.7) | 91(53.8) | .68 | .669 (.116–3.841 |  |
 G | 46 | 56 | .882 | 1.036 (.652–1.646) |  | ||
 T | 114 | 134 |  |  | |||