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Table 8 Genotype and allele frequencies of IL-β, IL17, IL10 and IL28 in influenza (A & B) and ILI groups
| Gene and genotype | Flu A & B (%) | ILI (%) | Crude p value | OR (95% CI) | Adjusted p value | ||
|---|---|---|---|---|---|---|---|
| IL-1β; rs16944 | |||||||
| AA | 7(22.6) | 24(77.4) | |||||
| GA | 71(51.4) | 67(48.6) | .007* | ||||
| GG | 2(33.3) | 4(66.7) | .027* | ||||
| GG vs. GA/AA | 2(33.3) | 78(46.2) | 4(66.7) | 91(53.8) | .689 | .547 (.096–3.127) | |
| AA vs. GG/GA | 7(22.6) | 73(50.7) | 24 (77.4) | 71(49.3) | .004* | .235 (.091–.610) | |
| A | 85 | 115 | .163 | 1.353 (.884–2.070) | |||
| G | 75 | 75 | |||||
| IL-17; rs2275913 | |||||||
| AA | 6(40) | 9(60) | |||||
| AG | 26(32.5) | 54(67.5) | .006* | .019* | |||
| GG | 44(57.9) | 32(42.1) | |||||
| GG vs. GA/AA | 44(57.9) | 32(33.7) | 32(42.1) | 63(66.3) | .002* | 2.589 (1.3714.889) | |
| AA vs. AG/GG | 6(40) | 70(44.9) | 9(60) | 86(55.1) | .717 | .810 (.266–2.467) | |
| A | 38 | 72 | .011* | 1.831 (1.144–2.928) | |||
| G | 114 | 118 | |||||
| IL-10; rs1800872 | |||||||
| GG | 4(50) | 4(50) | .760 | ||||
| TG | 72(48.3) | 77(51.7) | |||||
| TT | 4(36.4) | 7(63.6) | .510 | ||||
| TT vs. GG/TG | 4(36.4) | 76(48.4) | 7(63.6) | 81(51.6) | .439 | .619 (.170–2.256) | |
| GG vs. TG/TT | 4(50) | 76(47.5) | 4(50) | 84(52.5) | 1.000 | .731 (.168–3.178) | |
| G | 80 | 85 | .755 | .934 (.609–1.433) | |||
| T | 80 | 91 | |||||
| IL-28; rs8099917 | |||||||
| GG | 2(33.3) | 4(66.7) | |||||
| GT | 42(46.7) | 48(53.3) | .889 | ||||
| TT | 36(45.6) | 43(54.4) | .784 | ||||
| TT vs. GG/GT | 36(45.6) | 44(45.8) | 43(54.4) | 52(54.2) | .972 | .882 (.474–1.641) | |
| GG vs. GT/TT | 2(33.3) | 78(46.2) | 4(66.7) | 91(53.8) | .68 | .669 (.116–3.841 | |
| G | 46 | 56 | .882 | 1.036 (.652–1.646) | |||
| T | 114 | 134 | |||||
