Table 7 Genotype and allele frequencies of IL-β, IL17, IL10 and IL28 in influenza B and ILI groups
Gene and genotype/Allele | Flu B (%) | ILI (%) | Crude p value | OR (95%CI) | Adjusted P value | ||
|---|---|---|---|---|---|---|---|
IL-1β; rs16944 | |||||||
 AA | 1(4) | 24(96) |  |  |  | ||
 GA | 27(28.7) | 67(71.3) | .014* |  | .026* | ||
 GG | 2(33.3) | 4(66.7) |  |  |  | ||
 GG vs. GA/AA | 2(33.3) | 28(23.5) | 4(66.7) | 91(76.5) | .629 | 1.549 (.266 9.007) | .626 |
 AA vs. GG/GA | 1(4) | 29(29) | 24(96) | 71(71) | .009* | .101 (.013–.786) | .029 |
 A | 29 | 115 | .096 | 1.639(.914–2.939) |  | ||
 G | 31 | 75 |  |  |  | ||
IL-17; rs2275913 | |||||||
 AA | 3(25) | 9(75) | .176 |  | .305 | ||
 AG | 10(15.6) | 54(84.4) |  |  |  | ||
 GG | 14(30.4) | 32(69.6) |  |  |  | ||
 GG vs. GA/AA | 14(30.4) | 13(17.1) | 32(69.6) | 63(82.9) | .086 | 2.031 (.851 4.849) | .111 |
 AA vs. AG/GG | 3(25) | 24(21.8) | 9(75) | 86(78.2) | .801 | 1.227 (.301–4.994) | .775 |
 A | 16 | 72 | .264 | 1.449(.754–2.786) |  | ||
 G | 38 | 118 |  |  |  | ||
IL-10; rs1800872 | |||||||
 GG | 1(20) | 4(80) | .871 |  | .634 | ||
 TG | 28(26.7) | 77(73.3) |  |  |  | ||
 TT | 1(12.5) | 7(87.5) |  |  |  | ||
 TT vs. GG/TG | 1(12.5) | 29(26.4) | 7(87.5) | 81(73.6) | .385 | .391 (.046–3.353) | .391 |
 GG vs. TG/TT | 1(20) | 29(25.7) | 4(80) | 84(74.3) | 1.000 | .631 (.065–6.127) | .691 |
 T | 30 | 91 | .820 | 1.071(.596–1.924) |  | ||
 G | 30 | 85 |  |  |  | ||
IL-28; rs8099917 | |||||||
 GG | 0(0) | 4(100) |  |  | .244 | ||
 GT | 14(22.6) | 48(77.4) | .588 |  |  | ||
 TT | 16(27.1) | 43(72.9) |  |  |  | ||
 TT vs. GG/GT | 16(27.1) | 14(21.2) | 43(72.9) | 52(78.8) | .440 | 1.314 (.5693.036) | .522 |
 GG vs. GT/TT | 4(100) | 91(75.2) | 0(0) | 30(24.8) | .572 | .000 (.000 - NA) | .999 |
 T | 46 | 134 | .356 | .728(.371–1.430) |  | ||
 G | 14 | 56 |  |  |  | ||