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Table 7 Genotype and allele frequencies of IL-β, IL17, IL10 and IL28 in influenza B and ILI groups

From: Association of polymorphisms in inflammatory cytokines encoding genes with severe cases of influenza A/H1N1 and B in an Iranian population

Gene and genotype/Allele Flu B (%) ILI (%) Crude p value OR (95%CI) Adjusted P value
IL-1β; rs16944
 AA 1(4) 24(96)    
 GA 27(28.7) 67(71.3) .014*   .026*
 GG 2(33.3) 4(66.7)    
 GG vs. GA/AA 2(33.3) 28(23.5) 4(66.7) 91(76.5) .629 1.549 (.266 9.007) .626
 AA vs. GG/GA 1(4) 29(29) 24(96) 71(71) .009* .101 (.013–.786) .029
 A 29 115 .096 1.639(.914–2.939)  
 G 31 75    
IL-17; rs2275913
 AA 3(25) 9(75) .176   .305
 AG 10(15.6) 54(84.4)    
 GG 14(30.4) 32(69.6)    
 GG vs. GA/AA 14(30.4) 13(17.1) 32(69.6) 63(82.9) .086 2.031 (.851 4.849) .111
 AA vs. AG/GG 3(25) 24(21.8) 9(75) 86(78.2) .801 1.227 (.301–4.994) .775
 A 16 72 .264 1.449(.754–2.786)  
 G 38 118    
IL-10; rs1800872
 GG 1(20) 4(80) .871   .634
 TG 28(26.7) 77(73.3)    
 TT 1(12.5) 7(87.5)    
 TT vs. GG/TG 1(12.5) 29(26.4) 7(87.5) 81(73.6) .385 .391 (.046–3.353) .391
 GG vs. TG/TT 1(20) 29(25.7) 4(80) 84(74.3) 1.000 .631 (.065–6.127) .691
 T 30 91 .820 1.071(.596–1.924)  
 G 30 85    
IL-28; rs8099917
 GG 0(0) 4(100)    .244
 GT 14(22.6) 48(77.4) .588   
 TT 16(27.1) 43(72.9)    
 TT vs. GG/GT 16(27.1) 14(21.2) 43(72.9) 52(78.8) .440 1.314 (.5693.036) .522
 GG vs. GT/TT 4(100) 91(75.2) 0(0) 30(24.8) .572 .000 (.000 - NA) .999
 T 46 134 .356 .728(.371–1.430)  
 G 14 56    
  1. OR Odds ratio, CI Confidence interval (calculated by logistic regression model)
  2. p value is significant