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Fig. 3 | Virology Journal

Fig. 3

From: Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors

Fig. 3

Detection of HBsAg in the presence of anti-HBs. Native HBsAg was mixed with antibody from a vaccinee to achieve HBsAg concentrations of 0.06 IU/ml (a), 0.11 IU/ml (b), and 0.23 IU/ml (c) with concomitant final anti-HBs concentrations ranging from 0 to 10,000 mIU/ml. Samples were then tested in duplicate with the ARCHITECT Qual II and prototype HBsAg assays, Centaur HBsAg II, Elecys HBsAg II, and LIAISON XL MUREX HBsAg Quant. Quantitative results for the LIAISON assay were converted to S/CO values. S/CO values ≥ 1.0 are considered reactive by the respective assays

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