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Fig. 5 | Virology Journal

Fig. 5

From: Human papillomavirus type 16 E6 and E7 oncoproteins interact with the nuclear p53-binding protein 1 in an in vitro reconstructed 3D epithelium: new insights for the virus-induced DNA damage response

Fig. 5

E6 and E7 HPV16 oncoproteins interaction with 53BP1 proteins visualized with PLA technique. The red perinuclear punctuate dots visible in the CaSki (A-D) and E6E7 HPV16 NHEKs (B-E) are also present in the HPV16 reconstructed infected epithelium (C and F). Nuclei were always visualized in blue with DAPI counterstaining. Bar scales in 20x fields = 100 μm

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