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Fig. 3 | Virology Journal

Fig. 3

From: Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway

Fig. 3

PRRSV infection leads to MARC-145 cells cycle arrest at G2/M phase. MARC-145 cells mock- or 1 MOI PRRSV-infected were collected, and cell cycle was analyzed by PI staining and flow cytometry. a The DNA contents of MARC-145 cells at 0, 12, 24, 36, and 48 h post-infection were determined by PI staining and analyzed by flow cytometry. b Histogram represents the percentages of mock- and PRRSV-infected MARC-145 cells in G0/G1, S, and G2/M phases. Data are mean ± SEM from three independent experiments

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