Position
|
RAS
|
Genotype
|
Drug
|
---|
159
|
F
|
1a
|
SOF
|
237
|
G
|
1a
|
SOF
|
282
|
R/
T
|
1a
|
SOF
|
316
|
F
|
1a
|
SOF
|
320
|
F
|
1a
|
SOF
|
321
|
A
|
1a
|
SOF
|
159
|
F
|
1b
|
SOF
|
282
|
G/T
|
1b
|
SOF
|
316
|
F/H/N
|
1b
|
SOF
|
321
|
I
|
1b
|
SOF
|
314
|
H
|
1a
|
DSV
|
316
|
Y
|
1a
|
DSV
|
414
|
T/V
|
1a
|
DSV
|
448
|
C/H
|
1a
|
DSV
|
553
|
I
/V
|
1a
|
DSV
|
554
|
S
|
1a
|
DSV
|
556
|
G/N/R
|
1a
|
DSV
|
558
|
R
|
1a
|
DSV
|
559
|
G
|
1a
|
DSV
|
316
|
Y/
H
/N
|
1b
|
DSV
|
368
|
T
|
1b
|
DSV
|
414
|
I
|
1b
|
DSV
|
445
|
F
|
1b
|
DSV
|
448
|
C
|
1b
|
DSV
|
553
|
V
|
1b
|
DSV
|
556
|
G
|
1b
|
DSV
|
559
|
G/N
|
1b
|
DSV
|
421
|
V
|
1a
|
BCV
|
495
|
L/S
|
1a
|
BCV
|
499
|
A/any
|
1b
|
DLV
|
- BCV beclabuvir, DSV dasabuvir, SOF sofosbuvir, DLV deleobuvir
- Amino acid substitutions detected in vivo in DAA failing patients are underlined, independently of in vitro data availability. Additionally, RAS detected only in vitro are indicated in bold