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Table 1 Demographic and clinical characteristics of HMPV infection caused by different genotypes and sub-lineages

From: The role of human Metapneumovirus genetic diversity and nasopharyngeal viral load on symptom severity in adults

  HMPV Genotype HMPV Sub-lineage
Characteristics A, n = 40 B, n = 41 p A2b, n = 25 Unique A2
sub-lineage, n = 15
B1, n = 25 B2, n = 16 p
Sex
 Male, n = 29 13 16 0.540b 8 5 11 5 0.784b
 Female, n = 52 27 25   17 10 14 11  
Age
  < 65 years old, n = 65 32 33 0.956b 20 12 22 11 0.516b
  ≥ 65 years old, n = 16 8 8   5 3 3 5  
 mean (±SD) 45.28 ± 18.26 46.15 ± 20.12 0.839a 44.36 ± 18.68 46.80 ± 18.07 44.56 ± 17.63 48.63 ± 23.91 0.892c
Ethnicity
 Chinese, n = 19 12 7 0.402b 6 6 2 5 0.144b
 Malay, n = 38 18 20   15 3 14 6  
 Indian, n = 21 8 13   3 5 9 4  
 Others, n = 3 2 1   1 1 0 1  
Presence of Symptoms
 Sneezing, n = 56 29 27 0.517b 20 9 18 9 0.346b
 Nasal congestion, n = 54 23 31 0.084b 14 9 21 10 0.166b
 Nasal discharge, n = 58 31 27 0.245b 20 11 16 11 0.645b
 Cough, n = 80 40 40 0.320b 25 15 24 16 0.519b
 Sore throat, n = 59 28 31 0.570b 19 9 21 10 0.282b
 Hoarseness of voice, n = 72 36 36 0.753b 23 13 23 13 0.680b
 Muscle ache, n = 56 26 30 0.426b 17 9 18 12 0.812b
 Headache, n = 57 27 30 0.576b 15 12 18 12 0.541b
Estimated no. of days elapsed between symptom onset and enrollment date
  ≤ 1–2 days, n = 20 9 11 0.207b 5 4 7 4 0.600b
 3–5 days, n = 36 15 21   11 4 12 9  
  ≥ 6 days, n = 25 16 9   9 7 6 3  
 mean (±SD) 5.15 ± 3.63 4.12 ± 2.55 0.143a 4.56 ± 2.04 6.13 ± 5.28 4.20 ± 2.93 4.00 ± 1.80 0.211c
  1. n: number of patients, SD: standard deviation
  2. ap-value calculated by Independent Samples t-Test
  3. bp-value calculated by Pearson’s Chi-square test
  4. cp-value calculated by One-way ANOVA
  5. p = level of significance (2 tailed) at the 0.05 level