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Table 1 Demographic and clinical characteristics of HMPV infection caused by different genotypes and sub-lineages

From: The role of human Metapneumovirus genetic diversity and nasopharyngeal viral load on symptom severity in adults

 

HMPV Genotype

HMPV Sub-lineage

Characteristics

A, n = 40

B, n = 41

p

A2b, n = 25

Unique A2

sub-lineage, n = 15

B1, n = 25

B2, n = 16

p

Sex

 Male, n = 29

13

16

0.540b

8

5

11

5

0.784b

 Female, n = 52

27

25

 

17

10

14

11

 

Age

  < 65 years old, n = 65

32

33

0.956b

20

12

22

11

0.516b

  ≥ 65 years old, n = 16

8

8

 

5

3

3

5

 

 mean (±SD)

45.28 ± 18.26

46.15 ± 20.12

0.839a

44.36 ± 18.68

46.80 ± 18.07

44.56 ± 17.63

48.63 ± 23.91

0.892c

Ethnicity

 Chinese, n = 19

12

7

0.402b

6

6

2

5

0.144b

 Malay, n = 38

18

20

 

15

3

14

6

 

 Indian, n = 21

8

13

 

3

5

9

4

 

 Others, n = 3

2

1

 

1

1

0

1

 

Presence of Symptoms

 Sneezing, n = 56

29

27

0.517b

20

9

18

9

0.346b

 Nasal congestion, n = 54

23

31

0.084b

14

9

21

10

0.166b

 Nasal discharge, n = 58

31

27

0.245b

20

11

16

11

0.645b

 Cough, n = 80

40

40

0.320b

25

15

24

16

0.519b

 Sore throat, n = 59

28

31

0.570b

19

9

21

10

0.282b

 Hoarseness of voice, n = 72

36

36

0.753b

23

13

23

13

0.680b

 Muscle ache, n = 56

26

30

0.426b

17

9

18

12

0.812b

 Headache, n = 57

27

30

0.576b

15

12

18

12

0.541b

Estimated no. of days elapsed between symptom onset and enrollment date

  ≤ 1–2 days, n = 20

9

11

0.207b

5

4

7

4

0.600b

 3–5 days, n = 36

15

21

 

11

4

12

9

 

  ≥ 6 days, n = 25

16

9

 

9

7

6

3

 

 mean (±SD)

5.15 ± 3.63

4.12 ± 2.55

0.143a

4.56 ± 2.04

6.13 ± 5.28

4.20 ± 2.93

4.00 ± 1.80

0.211c

  1. n: number of patients, SD: standard deviation
  2. ap-value calculated by Independent Samples t-Test
  3. bp-value calculated by Pearson’s Chi-square test
  4. cp-value calculated by One-way ANOVA
  5. p = level of significance (2 tailed) at the 0.05 level