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Fig. 5 | Virology Journal

Fig. 5

From: The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model

Fig. 5

The plasmid backbone causes HBV clearance in unspecific manner. a WT mice received first hydrodynamic injection with NS, 20 μg pAAV/Control plasmid, or 20 μg pAAV/HBV1.2 plasmid, and then followed by second injection with 6 μg pAAV/HBV1.2 plasmid 1 week later. b Serum levels of HBsAg were determined at week 1 and 3 AHI. c Serum levels of HBsAg were detected at the indicated time points after hydrodynamical injection with 6 μg of pAAV/HBV1.2 mixing with or without 14 μg pRNT-H1.1 plasmids respectively. Results represent 2 independent experiments (n = 5–8/group)

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Virology Journal

ISSN: 1743-422X