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Table 1 Antiviral activity of CST against influenza virus strains

From: Cirsimaritin inhibits influenza A virus replication by downregulating the NF-κB signal transduction pathway

 

H1N1

H3N2

A/Fort Mon

mouth

/1/1947

A/Tianjin

Jinnan

/15/2009

A/JiangXi/

312/2006

 

TC50

IC50 (μg/ml)

SI

IC50 (μg/ml)

SI

IC50 (μg/ml)

SI

CST

153.3

6.3 ± 1.4

24.3

5.8 ± .22

26.4

11.1 ± 1.1

13.8

RBV

> 200

3.4 ± 0.2

58.8

6.0 ± 0.7

33.3

8.9 ± 0.5

22.5

  1. TC 50 50% toxicity concentration, IC 50 50% inhibitory concentration, SI selectivity index, SI = TC50/IC50;
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Virology Journal

ISSN: 1743-422X