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Table 1 Antiviral activity of CST against influenza virus strains

From: Cirsimaritin inhibits influenza A virus replication by downregulating the NF-κB signal transduction pathway

  H1N1 H3N2
A/Fort Mon
mouth
/1/1947
A/Tianjin
Jinnan
/15/2009
A/JiangXi/
312/2006
  TC50 IC50 (μg/ml) SI IC50 (μg/ml) SI IC50 (μg/ml) SI
CST 153.3 6.3 ± 1.4 24.3 5.8 ± .22 26.4 11.1 ± 1.1 13.8
RBV > 200 3.4 ± 0.2 58.8 6.0 ± 0.7 33.3 8.9 ± 0.5 22.5
  1. TC 50 50% toxicity concentration, IC 50 50% inhibitory concentration, SI selectivity index, SI = TC50/IC50;