Table 1 Characteristics of aVDPVs from Kamuli, Kween, and Kisoro districts of Uganda
From: The detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda
aVDPV (contact 1) | AFP case 1 | aVDPV (contact 2) | AFP case 2 | aVDPV (primary) | |
|---|---|---|---|---|---|
Place of isolation | Kamuli, 167 km from Kampala, Eastern Uganda | Kween, 299 km from Kampala, Eastern Uganda | Kisoro 481 km from Kampala, South-western Uganda, borders DRC | ||
Date of onset of paralysis (AFP case) | 13th Aug 2014 | 28th Jul 2014 | 18th May 2014 | ||
Date of laboratory confirmation of VDPV | 03rd Nov 2014 | 03rd Nov 2014 | 04th May 2016 | ||
OPV dose history | 1 | – | 4 | 2 (1 and 3) | 4 |
Last OPV dose | 02nd Jul 2014 | – | 18th Dec 2012 | 20th Nov 2012 | February 2015 |
Card seen? | Yes | – | Yes | Yes | – |
CD4 count /μl | 2548 | 3467 | 1417 | 1470 | Note done |
Age (months) | 4 | 39 | 24 | 26 | 1 |
Sex | M | M | M | F | F |
Stool conditions for the original specimens | One specimen delivered at 4-8 °C | Two specimens delivered at 4-8 °C | One specimen delivered at 4-8 °C | Two specimens delivered at 4-8 °C | Two specimens delivered at 4-8oC |
Relationship to the AFP case | Sibling | Not specified | Not applicable | ||
Injection given (date) | 11 & 12th Aug 2014 | aSeptember 2013 | none | ||
Diagnoses for the AFP case | Injection neuritis, left leg | Injection neuritis, right leg | Congenital abnormality, left arm | ||
On 60th day follow up of the AFP case | Completely recovered | Limp gait, right leg | Not done | ||
Proportion of cases (6 months to 15 years) with OPV3+ immunisation status ≥80% | 2011–75% 2012–67% 2013–100% 2014- - | 67% 60% 50% - | 0% 100% 38% - | ||
Non polio AFR rate (≥ 4/100,000) | 2011–1.59 2012–1.22 2013–0.79 2014–2.09 | 5.83 19.76 22.99 18.27 | 1.53 3.2 6.23 6.60 | ||
Stool adequacy ≥80% | 2011–75% 2012–67% 2013–50% 2014–20% | 92% 100% 50% 89% | 0% 100% 63% 88% | ||
Father’s occupation | Businessman | Businessman | Peasant | ||
Mother’s occupation | Housewife | – | – | ||
Residence population | Densely populated | Clusters of home steads | Spaced clusters of home steads | ||
Landscape | Flat | Mountainous terrain | Steep mountainous | ||
Visitors that came to the home recently | few | numerous | – | ||
Clean water source | No running water | No running water | 45% have clean water | ||
Vaccine supply | Not regular | – | Regular | ||
Sanitation | Poor conditions | Poor conditions | Good conditions | ||
30 household survey | 50% had received OPV for their age | 62% of the households surveyed had been fully immunised for poliovirus | Not done | ||
Health seeking behaviour of the community | Poor, negative beliefs about immunization | Poor health seeking behaviour, does not honour medical appointments | Good health seeking behaviour, seeks for treatment | ||