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Fig. 1 | Virology Journal

Fig. 1

From: Zika virus-induced hyper excitation precedes death of mouse primary neuron

Fig. 1

Electrophysiological analysis of mouse embryo primary neurons spontaneous activity. a Raster plots of 5 min spiking activity of neuronal cultures on Microelectrode array (MEA) at different days post infection (dpi). b Percentages of active electrodes (AE) and bursting electrodes (BE) during spontaneous neuronal activity recording at different dpi of mouse primary neuron cultures. c Mouse spontaneous spiking activity with average ratio of total spike (TS) number per electrode between 0 dpi (reference) and TS number at 2 and 7 dpi of spontaneous activity. Statistical differences were calculated with unpaired t tests by comparing uninfected group to infected groups unless indicated by bracket. *P < 0.05; **P < 0.01; ***P < 0.001; means ± SEM. For c n values are detailed in Additional file 7: Table S3

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