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Fig. 6 | Virology Journal

Fig. 6

From: Bat lung epithelial cells show greater host species-specific innate resistance than MDCK cells to human and avian influenza viruses

Fig. 6

Inhibition of the JAK/STAT pathway did not appear to affect virus output from infected bat cells. Cells were treated with 5 μM pyridone 6 (JAK inhibitor), for 20 h prior to infection with human USSR virus at 0.5 MOI. There was no notable difference in virus output between treated TB1-Lu, E. helvum and C. perspic cells, and their untreated counterparts. Pyridone 6 treated MDCK cells, however, showed a 2-fold increase in virus output. Results shown are representative of three experimental repeats

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