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Table 2 Genotype frequency of SNP rs12979860 and rs8099917 in both populations

From: IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in Uruguayan patients

IL28B SNP

HCV-infected population (n = 78)

Uninfected population (n = 92)

Statistical test and value

p value

rs12979860, n (%)

  

χ2cd 6.185

0.045*

 CC

23 (29.5)

42 (45.7)

  

 CT

37 (47.4)

39 (42.4)

  

 TT

18 (23.1)

11 (11.9)

  

 CT + TT d

55 (70.5)

50 (54.3)

χ2d 4.671

0.031*

 CC + CT r

60 (76.9)

81 (88.0)

χ2r 3.689

0.055

rs 8,099,917, n(%)

  

χ2cd 3.850

0.146

 TT

45 (57.7)

56 (60.9)

  

 TG

22 (28.2)

31 (33.7)

  

 GG

11 (14.1)

5 (5.4)

  

TG + GG d

33 (42.3)

36 (39.1)

χ2d 0.177

0.674

TT + TG r

67 (85.9)

87 (94.6)

χ2r 3.720

0.054

  1. χ2 Chi-square test; cd = Codominant model; d = Dominant model; r = Recessive model; *p < 0.05