Table 1 Anti-NS1 monoclonal antibodies isotype, epitope and reactivity to DENV1–4 NS1. Isotype, epitope type and iELISA results of six anti-NS1 DENV-4 monoclonal antibodies
MAb | Isotype | Epitope | iELISA (reactivity of MAbs to recombinant flavivirus NS1) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
rNS1 DENV1 | rNS1 DENV2 | rNS1 DENV3 | rNS1 DENV4 | rNS1 WNV | rNS1 YFV | SUMO | SUMO*-NS1 fusion protein | |||
10H8F7 | IgG2b/K | Linear | – | – | – | – | – | – | + | + |
4B6C10 | IgG2b/K | Linear | – | – | – | – | – | – | + | + |
3H7A9 | IgG2b/K | Linear | – | – | – | + | – | – | – | + |
8A6F2 | IgG2b/K | Linear | – | – | – | + | – | – | – | + |
10H10B5 | IgG2b/K | Linear | – | – | – | – | – | – | + | + |
6D4B10 | IgG2b/K | Linear | – | – | – | + | – | – | – | + |