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Table 1 Sensitivity and specificity for selected cutoff values

From: Evaluation of a method to measure HHV-6B infection in vitro based on cell size

Size measurement approach

Size of individual cells

Average size

Infection day (dpi)

4

7

4

7

Cutoff value (μm)a

13.9

14.3 (13.9)

14.2 (13.5)

13.5

Sensitivityb

0.77

0.66 (0.69)

0.93 (0.96)

1.00

False negativesc

23%

34% (31%)

7% (4%)

0%

Specificityb

0.87

0.91 (0.87)

1.00 (0.96)

0.96

False positivesc

13%

9% (13%)

0% (4%)

4%

  1. aCutoff value for maximized product of sensitivity and specificity for each size measurement approach and infection day (dpi); in parenthesis, a consensus cutoff value for each size measurement approach is shown. bSensitivity and specificity at each cutoff value; in parenthesis, sensitivity and specificity associated with the consensus cutoff values. cPercentage of false negatives and false positives at each cutoff values; in parenthesis, values for consensus cutoff values
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Virology Journal

ISSN: 1743-422X