The prevalent status and genetic diversity of porcine reproductive and respiratory syndrome virus in China: a molecular epidemiological perspective

Table 2 The recombinant virus strains and the recombination regions

No.	Recombinant strains	Major parent	Minor parent	Recombination regions	Virulence	Reference
1	JL580^a	NADC30^a	HP-PRRSV (09HEN1)	Nsp2, Nsp3~Nsp7, ORF2a~ORF4	Highly Pathogenic	[23]
2	FJ1402^a	NADC30^a	HP-PRRSV (GD)	Nsp2~Nsp3, Nsp12~ORF3	Highly Pathogenic	[47]
3	HENAN-HEB^a	15HEN1^a	HP-PRRSV (JXA1)	Nsp2		[48]
4	TJnh1501^a	CHsx1401^a	TJbd14-1^b	Nsp2	intermediate virulence	[49]
5	FJW05^a	JXA1-P80^b	FJZ03^a	Nsp1-ORF5	Highly Pathogenic	[50]
6	FJXS15^a	JXA1-P80^b	FJZ03^a	Nsp1-ORF5	Highly Pathogenic	[51]
7	HNhx^a	HENAN-HEB^a	HP-PRRSV (JXA1)	Nsp4~Nsp9		[46]
8	HNyc15^a	15SC3^a	CH-1a/VR2332	ORF2~ORF4		[52]
9	HENAN-XINX^a	NADC30^a	VR-2332	Nsp2~Nsp5		[48]
10	Chsx1401^a	HENAN-XINX^a	VR-2332	Nsp11	intermediate virulence	[49]
11	SY0909	HP-PRRSV (JXA1)	NT0801	Nsp12~ORF5		This study
12	GDsg	QYYZ	JXA1-P80^b	Nsp9~Nsp11		[82]
13	GM2	QYYZ	RespPRRS MLV^b	Nsp7~Nsp11		[54]
14	HB-1(sh)/2002	HB-1/3.9c	CH-1a	ORF2a~ORF4		This study
15	HNjz15	/	/	/	intermediate virulence	[55]

“^a” means NADC30 or NADC30-like virus strains. “^b” indicates modified live vaccine strains or vaccine derivative strain. The recombination events were detected by RDP4 program using seven different algorithms (RDP, GeneConv, BootScan, MaxChi, Chimera, SiScanm and 3Seq)