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Table 1 Characteristics of study subjects and comparison between anti-HEV IgM positive and IgM negative group

From: Prevalence and risk of hepatitis E virus infection in the HIV population of Nepal

Characteristics/ Variables Total HIV+ subjects (N = 459) N (%) or mean ± SD Anti-HEV IgM+(N = 70) N (%) or mean ± SD Anti-HEV IgM–(N = 389) N (%) or mean ± SD P valueb
Age 36.21 ± 10.35 37.41 ± 11.02 35.99 ± 10.19 0.318
Gender (Male) 274 (59.69) 40 (57.14) 234 (60.15) 0.510c
Duration of HIV Diagnosis (years) 4.12 ± 2.57 4.57 ± 2.6 4.04 ± 2.56 0.081d
Living in Kathmandu Valley 198 (43.13) 57 (81.42) 141 (36.24) <0.001c,a
CD4+ count (cells/μL) 301.97 ± 117.75 351.73 ± 109.78 293.02 ± 117.03 <0.001a
ALT 32 ± 12.39 53.9 ± 19.80 28.75 ± 3.79 <0.001a
AST 35 ± 8.15 42.77 ± 14.85 33.60 ± 5.13 <0.001a
HBsAg (n) 24 (5.2) 10 (14.28) 14 (3.59) <0.001c,a
Anti HCV (n) 342 (74.50) 27 (38.57) 315 (80.97) <0.001c,a
Anti-HEV IgG (n) 181 (39.43) 17 (24.28) 164 (42.15) 0.005c, a
HIV Viral load in log cps/ml 2.74 ± 0.46 2.90 ± 0.61 2.71 ± 0.44 0.016a
  1. Abbreviations: CD4- Cluster of differentiations 4; ALT- Alanine aminotransferase; AST- Aspartate aminotransferase; GGT- Gamma glutamyltranspeptidase; HBsAg- Hepatitis B surface Antigen; HCV- Hepatitis C virus, HEV- Hepatitis E virus, HIV- Human Immunodeficiency virus
  2. aSignificant
  3. bSignificance of difference between anti-HEV IgM+ and IgM– group
  4. cChi squared test
  5. dMann Whitney U test