Fig. 6

Molecular Docking. a Binding pose of geraniin’s molecular structure on DENV-2 E protein (PDB entry: 1OKE). Arrow indicates the molecular structure of geraniin. Domain III is marked blue and a putative receptor-binding loop in domain III is marked red. b Interaction of geraniin with the amino acid residues of DENV-2 E protein as shown by docking. Geraniin binds at domain III of E protein which ranges from amino acid residues 296–394, by forming a hydrogen bond with the amino acid residues of the E protein