Table 5 Evaluation of different nucleic acid amplification and detection systems in regard to their performance and suitability as POC tests (+++ = good; ++ = medium; + = weak)
From: Development of molecular confirmation tools for swift and easy rabies diagnostics
R14 RT-qPCR | HighSpeed RT-qPCR | RT-RPA | |
|---|---|---|---|
Equipment costs | + | + | ++ |
Equipment size | ++ | ++ | +++ |
Reagent costs | ++ | +++ | + |
Reagent stability | + | + | +++ |
Rapid assay design | ++ | ++ | + |
Reaction speed | + | ++ | +++ |
Robustness | +++ | +++ | ++ |
Sensitivity | +++ | ++ | + |
Specificity | ++ | ++ | ++ |