Fig. 9

Cross neutralizing antibody (NA) titers of the rHuN4-F112-inoculated piglet sera against different rescued viruses. a-f The NA titers or cross NA titers of rHuN4-F112-inoculated piglet sera (#11, #12, #13, #14, #15 and #16) against rHuN4-F112, rHuN4-F112-C1a, rHuN4-F112-C1b, rHuN4-F112-C27, rCH-1R, rCH-1R-H1a, rCH-1R-H1b and rCH-1R-H27. All the serum samples were collected at 9 weeks post-inoculation with rHuN4-F112. An asterisk (*) indicates a significant difference in the NA titers between two different rescued viruses (*P < 0.05; **P < 0.01; ***P < 0.001). The neutralization tests of each serum sample were repeated three times independently. The results represent the average of the duplicates