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Fig. 10 | Virology Journal

Fig. 10

From: A novel bladder cancer - specific oncolytic adenovirus by CD46 and its effect combined with cisplatin against cancer cells of CAR negative expression

Fig. 10

The apoptosis-related proteins expression on bladder cancer cells treated with cisplatin and Ad5/F11p. The 5637, EJ, and T24cells bladder cancer cells were treated with Ad5/F11p-PSCAE-UPII-E1A (10 MOI) alone, cisplatin (1 μg/ml) alone, Ad5/F11p-PSCAE-UPII-E1A (10 MOI) plus cisplatin (1 μg/ml), or PBS for 48 h respectively, and then assessed the expression of apoptosis-related proteins by Western blot analysis. The housekeeping genesβ-actin was viewed as internal reference. Ad5/F11p represented Ad5/F11p-PSCAE-UPII-E1A and combined represented Ad5/F11p-PSCAE-UPII-E1A plus cisplatin.

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Virology Journal

ISSN: 1743-422X