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Fig. 2 | Virology Journal

Fig. 2

From: Arsenic trioxide inhibits EBV reactivation and promotes cell death in EBV-positive lymphoma cells

Fig. 2

ATO inhibits EBV genomic DNA replication. a Mutu cells were treated with 1 nM of ATO for 3 days and cell media was harvested for viral genome extraction. PCR was performed using primers spanning the BamHI Z fragment of the EBV genome, * p < 0.05 vs. NT. b EBV-positive cells, Mutu (M), JY (J), BX-1(B), and Akata (A) cells were treated with 1 nM of ATO for 5 days and cellular total DNA was extracted for PCR using primers spanning the BamHI Z region and the Qp region of EBV genome, * p < 0.05 vs. NT. The relative expression of BamHI Z and Qp was calculated using the comparative Ct method (2–∆∆CT)

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