Fig. 4

Motif analysis a. Phosphorylation motifs and sequence probability logos of remarkably modulated phosphorylation site motifs for ±6 amino acids around the phosphorylation sites. Motif score is obtained based on residues proximal to the fixed residues using the motif’s Position Weight Matrix (PWM). Background size indicates to the number of peptides identified and background matches indicate to the number of peptides containing the specific motif. Foreground size indicates to the number of phosphorylated peptides identified and foreground matches indicate to the number of phosphorylated peptides containing the specific motif. b The amino acid compositions heat map of phosphorylated sites representing the frequency of different kinds of amino acids around the phosphorylated sites. The colors represent the log₁₀ of the ratio of amino acid frequency within 13 residues from the pS (phosphorylated Serine) residue versus S, red shows enrichment and green shows depletion