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Table 1 The distribution by number and (proportions), of viral tropism across HIV subtype variants using Geno2Pheno at three cut-off points

From: Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART

Viral Tropism at FPR cut-off

 

FPR, 5%

FPR (10%)

FPR (20%)

TOTAL

HIV-1 Subtype

CCR5,

CXCR4,

CCR5,

CXCR4,

CCR5,

CXCR4, N

A1

31 (86.1%)

5 (13.9%)

29 (80.6)

7 (19.4)

26 (72.2)

10 (27.8)

36 (100)

aA1r.

6 (77.8)

1 (22.2)

6 (85.7)

1 (14.3)

6 (85.7)

1 (14.3)

7 (100)

A2

2 (50)

2 (50)

2 (50)

2 (50)

2 (50)

2 (50)

4 (100)

C

5 (100)

0 (0)

5 (100)

0 (0)

5 (100)

0 (0)

5 (100)

D

2 (40)

3 (60)

1 (20)

4 (80)

0 (0)

5 (100)

5 (100)

χ2 p value

0.045

0.016

0.005

Total

46 (81)

11 (19)

43 (75)

14 (25)

39 (68)

18 (32)

57 (100)

  1. aA1r, recombinants of subtype A1. The A1 recombinants included A1D (3), A1A2 (2),A1H (1), A1A2D (1). The number of sequence isolates for each category of co-receptor tropism is shown followed by the percentages in parentheses. P-value is derived from cross-tabulation of co-receptor tropism and virus subtype