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Fig. 2 | Virology Journal

Fig. 2

From: The intranasal adjuvant Endocine™ enhances both systemic and mucosal immune responses in aged mice immunized with influenza antigen

Fig. 2

Evaluation of influenza-specific IgG responses. Mice were vaccinated intranasally or subcutaneously three times with three week intervals using split influenza antigen (A/California/07/2009(H1N1)pdm) formulated with or without the adjuvant Endocine™. Influenza-specific (a) serum IgG, IgG1 and IgG2a endpoint titers (GMT ± CI95), (b) serum IgG titer (median) over time and (c) IgG titers (GMT) in lung homogenates are shown. Significant differences to the adjuvanted vaccine group is indicated by *p < 0.05, **p < 0.01, ***p < 0.001

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