Fig. 1From: The intranasal adjuvant Endocine™ enhances both systemic and mucosal immune responses in aged mice immunized with influenza antigenEvaluation of HI response. Mice were vaccinated intranasally or subcutaneously three times with three week intervals using split influenza antigen (A/California/07/2009(H1N1)pdm) formulated with or without the adjuvant Endocine™. a Individual HI titers (GMT) at day 63 and (b) HI titers (median) over time. Significant differences to the adjuvanted vaccine group is indicated by *p < 0.05, **p < 0.01, ***p < 0.001Back to article page