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Fig. 3 | Virology Journal

Fig. 3

From: Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques

Fig. 3

a Plasma viral load and number of antigens responsible for IgG responses were plotted for each macaque over the course of 257 days for intravaginally and 272 days for intrarectally SIVMAC251 infected macaques. Each bar represents breadth (the number of antigens (Env, Gag, Tat and/or Nef) positive in any combination for IgG responses) at that specific time point. Absence of any bar represents no antigen-specific IgG responses detected for that time point. b Pearson coefficient of determination analysis between plasma viral load and breadth of IgG responses were shown for all macaques following SIVMAC251 inoculation for all time points. Note, GN91 had significant correlation values that were shown in bold numbers. Animal AE14 had no detectable IgG responses upto 236dpi against any SIV antigen and therefore no value of correlation was determined. R and P denote Pearson R and probability values respectively for each animal when correlated with plasma viral load. P value <0.05 was considered significant

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