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Table 3 Nucleotide sequence mutation at L2 of 8 HPV-33 isolates

From: L1 and L2 gene polymorphisms in HPV-58 and HPV-33: implications for vaccine design and diagnosis

Sequence pattern

HPV33 L2 Nucleotide sequence

n

Sub-lineages

 

4

4

4

4

5

5

5

5

5

5

5

5

  
 

4

6

8

9

0

0

2

2

2

3

3

4

  
 

3

7

0

0

2

5

2

5

8

1

2

5

  
 

8

1

9

5

6

1

0

7

7

4

4

7

  

M12732

G

T

C

C

A

T

C

G

G

G

A

C

  

KU518344

-

-

-

-

-

-

T

-

-

-

-

-

73

A1

KU518345

-

-

-

-

-

-

T

-

-

A

-

-

3

A1

KU518346

-

-

-

-

-

-

T

-

-

-

-

T

1

A1

KU518347

-

-

-

-

G

 

T

-

-

-

-

-

1

A1

KU518348

-

-

-

-

-

A

T

-

-

-

-

-

8

A1

KU518349

A

-

-

-

-

-

T

-

-

-

-

-

6

A1

KU518350

A

-

A

T

-

-

T

-

-

-

-

-

3

A1

KU518351

A

C

-

T

-

-

T

C

A

-

C

-

6

A2

     

I

F

 

D

D

D

N

   
 

D

   

2

2

 

3

3

3

3

   

aa mutation

7

-

-

-

7

8

-

5

6

6

7

-

101

 
 

7

   

3

1

 

0

0

9

2

   
 

N

   

V

Y

 

H

N

N

T

   

second struture

-

S

-

S

-

-

-

-

-

-

-

-

  
  1. Note: M12732 was used as reference. The nucleotides conserved with respect to the reference sequence are marked with a dash(-), whereas a variation position was indicated by a letter. Predicted amino acid changes were also shown. The “S” in the last row of the table means Sheet, the “H” means Helix